Synthesis and characterization of castor oil-derived oxidation-responsive amphiphilic block copolymers: Poly(ethylene glycol)-b-poly(11-((2-hydroxyethyl)thio)undecanoate)

European Polymer Journal(2020)

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摘要
•A renewable ω-hydroxyalkanoic acid sulphur-containing monomer is described.•Homo- and copolyesters by CALB-catalyzed polycondensation have been obtained.•Amphiphilic polyesters were obtained by polycondensation with Me-polyethyleneglycol.•The PEG-derived polyesters self-assemble to form micelles in aqueous solution.•Oxidative and disassembling behaviour using H2O2 has been studied.
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关键词
Sulfur-containing polyester,Amphiphilic polymer,Renewable resource,Enzymatic polycondensation,Oxidation-responsive,Drug delivery
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