NON-FAMILIAL HYPERTROPHIC CARDIOMYOPATHY: PREVALENCE, NATURAL HISTORY AND CLINICAL IMPLICATIONS

Jodie Ingles,Charlotte Burns,Richard Bagnall,Lien Lam,Laura Yeates,Tanya Sarina, Raj Puranik,Tom Briffa,John Atherton,Tim Driscoll,Christopher Semsarian

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2017）

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摘要

Background: The yield of positive sarcomere mutations in hypertrophic cardiomyopathy (HCM) is increased in probands with a family history of disease, younger age and asymmetric septal morphology, suggesting different clinical subgroups of disease occur. We hypothesized probands with no family

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