Genomic characterization of malignant pleural mesothelioma and associated clinical outcomes.

Paul Markowitz,Malini Patel,Roman Groisberg,Joseph Aisner,Salma K Jabbour,Subhajyoti De,Shridar Ganesan,Jyoti Malhotra

Cancer treatment and research communications（2020）

引用 9|浏览22

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摘要

Our study has identified that TP53 confers worse survival and response to platinum chemotherapy compared to BAP1. Overall PDL1 expression and TMB is low in patients with MPM resulting in limited benefit from single agent PD-1/PD-L1 agent.

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Genomic,Mesothelioma,Mutation burden

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