Lysozyme: A Double-Edged Sword In The Intestine
TRENDS IN IMMUNOLOGY(2020)
摘要
Lysozyme-secreting Paneth cells are abnormally present in the distal colons of patients with inflammatory bowel disease (IBD), along with high amounts of lysozyme in feces. In a recent article in Immunity, Yu et al. show that lysozyme-mediated processing of luminal bacteria in the colon triggers a proinflammatory response and predisposes mice to experimental IBD.
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关键词
colitis,immune response,inflammatory bowel diseases,lysozyme,microbiota
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