Candida colonization as a predictor of invasive candidiasis in non-neutropenic ICU patients with sepsis: A systematic review and meta-analysis

•Candida colonization is associated with an increased chance of invasive Candida infection as a cause of sepsis in critically ill patients.•A lack of history of Candida colonization is helpful to rule out Candida as a cause of sepsis.•A history of Candida colonization has a low positive predictive value for ruling in Candida as a cause of sepsis.