Association of early nasopharyngeal immune markers with COVID 19 clinical outcome: predictive value of CCL2/MCP 1

Open Forum Infectious Diseases(2020)

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摘要
Early recognition of severe forms of coronavirus disease 2019 (COVID-19) is essential for an opportune and effective intervention, reducing life-risking complications. An altered inflammatory immune response seems to be associated with COVID-19's pathogenesis and progression to severity. Here we demonstrate the utility of early nasopharyngeal swab samples for detection of the early expression of immune markers and the potential value of CCL2/MCP-1 in predicting disease outcome.
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关键词
COVID-19, chemokines, cytokines, inflammation, prognostic biomarkers
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