Methylene blue reduces incidence of early postoperative cognitive disorders in elderly patients undergoing major non-cardiac surgery: An open–label randomized controlled clinical trial
Journal of Clinical Anesthesia(2021)
摘要
•POD and POCD are common complication after major surgery in elderly patients.•MB may be effective for preventing early postoperative neurocognitive disorders.•2 mg/kg intravenous MB can be safely used during perioperative period.
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关键词
Methylene blue,Postoperative delirium (POD),Postoperative cognitive dysfunction (POCD),Elderly patients,Major surgery
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