Prenatal Alcohol Exposure and Chorioamnionitis Results in Microstructural Brain Injury in a Preclinical Investigation.

Jessie R Maxwell,Tracylyn R Yellowhair,Suzy Davies, Danny A Rogers,Krystle L McCarson,Daniel D Savage,Lauren L Jantzie

Annals of pediatric research（2020）

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摘要

The combination of moderate PAE+CHORIO results in an increased mortality, concomitant with diffuse microstructural brain injury noted in young adolescent offspring at PD28. Future studies should examine the extent to which PAE exacerbates the damage caused by CHORIO alone and whether these deficits persist into adulthood.

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关键词

Chorioamnionitis,Diffusion tensor imaging,Frontal cortex,Prenatal alcohol exposure

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