Identification Of A Polymorphism In The N Gene Of Sars-Cov-2 That Adversely Impacts Detection By Reverse Transcription-Pcr
JOURNAL OF CLINICAL MICROBIOLOGY（2021）
摘要
Since April 7, 2020, our COVID-19 diagnostic laboratory (CLIAHUB) has received samples from multiple counties in California - our RT-PCR protocol (1) employs N-gene (NIID_2019-nCov_N_F2/R2ver3/P2 (Japan) (2)) and E-gene (E_Sarbeco_F/R/P1 (Germany) (3)) simplex assays.….
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关键词
COVID-19, PCR, SARS-CoV-2, diagnosis, mutation, polymorphism, sensitivity
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