Serotype distribution and antimicrobial susceptibility of Streptococcus pneumoniae associated with invasive pneumococcal disease among adults in Japan

Katsunori Yanagihara,Kosuke Kosai,Hiroshige Mikamo,Hiroshi Mukae,Yoshio Takesue,Machiko Abe,Kazuko Taniguchi,Tanaz Petigara,Mitsuo Kaku

International Journal of Infectious Diseases（2021）

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摘要

•S. pneumoniae isolates were collected from adults with invasive pneumococcal disease (IPD) in Japan.•Prevalence of invasive pneumococcal disease caused by PPV23 serotypes was 61%.•Low prevalence of invasive pneumococcal disease caused by PCV7 and PCV13 serotypes.•Non-vaccine serotypes accounted for 37.9% of all isolates.•Improved vaccination rates and next-generation vaccines are warranted in Japan.

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关键词

Invasive pneumococcal disease,Antimicrobial susceptibility,Japan,Pneumococcal vaccines,Streptococcus pneumonia,Serotyping

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