Activation of EphrinB2 Signaling Promotes Adaptive Venous Remodeling in Murine Arteriovenous Fistulae

Tun Wang,Jia Liu,Haiyang Liu,Shin-Rong Lee,Luis Gonzalez,Jolanta Gorecka,Chang Shu,Alan Dardik

Journal of Surgical Research（2021）

引用 4|浏览12

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摘要

•EphrinB2 signaling contributes to adult venous remodeling during arteriovenous fistula maturation.•Activated EphrinB2 increases the activity of venous signaling pathways.•EphrinB2 may be a potential therapeutic target to improve fistula maturation.

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关键词

Arteriovenous fistulae,EphrinB2,Reverse signaling,EphB4,Venous remodeling,Endothelial cells

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