1,8-Naphthyridine Derivatives: A Privileged Scaffold For Versatile Biological Activities

MINI-REVIEWS IN MEDICINAL CHEMISTRY(2021)

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摘要
1, 8- Naphthyridine nucleus belongs to significant nitrogen-containing heterocyclic compounds which has garnered the interest of researchers due to its versatile biological activities. It is known to be used as an antimicrobial, anti-psychotic, anti-depressant, anti-convulsant, anti-Alzheimer's, anti-cancer, analgesic, anti-inflammatory, antioxidant, anti-viral, anti-hypertensive, antimalarial, pesticides, anti-platelets, and CB2 receptor agonist, etc. The present review highlights the framework of biological properties of synthesized 1, 8-naphthyridine derivatives developed by various research groups across the globe.
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关键词
1,8-Naphthyridine derivatives, nalidixic acid, gemifloxacin, enoxacin, voreloxin, tosufolxacin
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