Physically-Based Simulation and Web Visualization of C. elegans Behavioural Experiments

This paper presents the work done in the framework of the Si elegans project to develop the physics engine for the simulation of the roundworm Caenorhabditis elegans and the interfaces to define and visualize behavioural experiments of the worm. The physically-based simulation of the locomotion of the worm is guided by a biomechanical model, based on anatomically matched biphasic springs. The simulation is presented via an experiment visualization web, using a 3D motion reproduction obtained through animation bones. This web also displays information about the activation in muscles and neurons, on additional information panels. Finally, an experiment definition portal has been developed where, by means of a timeline, the user can easily design complex experimental assays.