Infiltration of M2 Macrophages and Regulatory T Cells Plays a Role in Recurrence of Renal Cell Carcinoma

Sabina Davidsson,Michelangelo Fiorentino,Francesca Giunchi,Margareta Eriksson,Ann Erlandsson,Pernilla Sundqvist,Jessica Carlsson

European Urology Open Science（2020）

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摘要

Regulatory T cells (Tregs) and M2 macrophages have been hypothesized to contribute to tumor progression. We found that M2 macrophages and Tregs are associated with more aggressive renal cell carcinoma, and that they have a synergistic effect on clinical outcome.

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关键词

Renal cell carcinoma,Immunohistochemistry,CD163+ M2 macrophages,FOXP3+ regulatory T cells

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