Use Of Anti-Il-17 Monoclonal Antibodies In Hiv Patients With Erythrodermic Psoriasis

Mary Catherine G. Pangilinan,Peerada Sermswan,Pravit Asawanonda

CASE REPORTS IN DERMATOLOGY(2020)

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摘要
Psoriasis is an immune-mediated skin disease with various presentations. HIV infection affects the immune system and aggravates psoriasis lesions. Therefore, psoriasis management in HIV patients poses a great challenge for dermatologists. In this report, 2 HIV patients with erythrodermic psoriasis received anti-IL-17 and experienced significant clearance of lesions. No recurrence or opportunistic infection was noted. In conclusion, anti-IL-17 monoclonal antibodies are an effective and promising treatment option for HIV-infected patients with psoriasis.
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关键词
Biologic treatment, Ixekizumab, Secukinumab, HIV psoriasis, Anti-IL-17, Erythrodermic psoriasis
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