miRNA profile of extracellular vesicles isolated from saliva of Haemaphysalis longicornis tick

Mohsin Nawaz,Muhammad Irfan Malik,Houshuang Zhang, Mebrathu Berhe Gebremedhin,Jie Cao,Yongzhi Zhou,Jinlin Zhou

Acta Tropica（2020）

引用 16|浏览8

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摘要

•Saliva of partially engorged Haemaphysalis longicornis ticks was examined for the presence of miRNA containing EVs.•RNA-seq analysis showed that tick-derived EVs contained small non-coding RNA populations including miRNAs.•The analysis of tick-derived EVs identified 36 known miRNAs, 34 novel miRNAs and 842 novel piRNA.•Vesicles could transfer these miRNAs to invade host cell functions.

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关键词

Haemaphysalis longicornis,Extracellular vesicles,Saliva,miRNAs,Tick-borne pathogens

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