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Massively parallel quantification of CRISPR editing in cells by TRAP-seq enables better design of Cas9, ABE, CBE gRNAs of high efficiency and accuracy

Xi Xiang,Kunli Qu,Xue Liang,Xiaoguang Pan,Jun Wang,Peng Han,Zhanying Dong,Lijun Liu,Jiayan Zhong,Tao Ma, Yiqing Wang,Jiaying Yu,Xiaoying Zhao,Siyuan Li,Zhe Xu,Jinbao Wang,Xiuqing Zhang,Hui Jiang,Fengping Xu,Lijin Zou,Huajing Teng,Xin Liu,Xun Xu,Jian Wang,Huanming Yang,Lars Bolund,George M. Church,Lin Lin,Yonglun Luo

biorxiv（2020）

Cited 3|Views48
Key words
Gene editing,A-to-G base editing,C-to-T base editing,Genome engineering,System biology
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