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Sulfopin, a selective covalent inhibitor of Pin1, blocks Myc-driven tumor initiation and growth in vivo

Christian Dubiella,Benika J. Pinch,Daniel Zaidman,Theresa D. Manz,Evon Poon,Shuning He,Efrat Resnick,Ellen M. Langer,Colin J. Daniel,Hyuk-Soo Seo,Ying Chen,Scott B. Ficarro,Yann Jamin,Xiaolan Lian,Shin Kibe,Shingo Kozono,Kazuhiro Koikawa,Zainab M. Doctor,Behnam Nabet,Christopher M. Browne,Annan Yang,Liat Stoler-Barak,Richa B. Shah,Nick E. Vangos,Ezekiel A. Geffken,Roni Oren,Samuel Sidi,Ziv Shulman,Chu Wang,Jarrod A. Marto,Sirano Dhe-Paganon,Thomas Look,Xiao Zhen Zhou,Kun Ping Lu,Rosalie C. Sears,Louis Chesler,Nathanael S. Gray,Nir London

biorxiv（2020）

Cited 6|Views84
Key words
covalent fragments,covalent probes,Pin1,neuroblastoma,Myc
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