Reducing FASN expression sensitizes acute myeloid leukemia cells to differentiation therapy

Magali Humbert,Kristina Seiler,Severin Mosimann,Vreni Rentsch,Sharon L. McKenna,Mario P. Tschan

biorxiv（2020）

引用 23|浏览27

暂无评分

摘要

Together, our data demonstrate that inhibition of FASN expression in combination with ATRA treatment facilitates granulocytic differentiation of APL cells and may extend differentiation therapy to non-APL AML cells.

查看译文

关键词

FASN,AML,ATRA,TFEB,mTOR,autophagy

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要