In Silico Design of Phl P 6 Variants with Altered Fold-Stability Significantly Impacts Antigen Processing, Immunogenicity and Immune Polarization.

Petra Winter,Stefan Stubenvoll,Sandra Scheiblhofer,Isabella A. Joubert,Lisa Strasser, Carolin Briganser,Wai Tuck Soh,Florian Hofer,Anna Sophia Kamenik,Valentin Dietrich,Sara Michelini,Josef Laimer,Peter Lackner,Jutta Horejs-Hoeck,Martin Tollinger,Klaus R. Liedl,Johann Brandstetter,Christian G. Huber,Richard Weiss

Frontiers in Immunology（2020）

引用 10|浏览35

关键词

structural stability,endolysosomal degradation,antigen processing and presentation,protein stabilization,immune polarization,in silicomutagenesis,in silicomutant screening

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