Anomalous aortic origin of coronary artery biomechanical modeling: Toward clinical application

CCTA of patients with AAORCA is transformed into a 3-dimensional computational representation by extracting a set of 25 parameters. The model is pressurized to simulate a physical effort condition, and through structural FEA, we estimate the luminal diameter changes along the vessel. The anomalous coronary artery shows an inability to expand the lumen under pressure-loading conditions, mainly in the intramural segment. Evaluation of such impaired expansion using simulation may allow evaluating coronary changes during effort.