Loss of cyclin A2 in murine colonic epithelial cells disrupts colon homeostasis by triggering DNA damage and dysplasia and high cyclin A2 expression is a good-prognosis factor in patients with colorectal cancer

biorxiv(2019)

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关键词
cyclin A2,murine colitis-associated cancer model,colorectal cancer (CRC),DNA damage,regenerative pathways,dysplasia,Consensus Molecular Subtypes (CMS),prognosis.
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