Genomic Instability And Mitochondrial Homeostasis In Cancer: Does Chromatin Have A Say?
MOLECULAR & CELLULAR ONCOLOGY(2020)
摘要
While genomic instability and mitochondrial homeostasis are integral for cancer progression, how these two hallmarks interact remains poorly understood. Here, we reflect on the dialogue between chromatin-based genomic instability and impairment of mitochondrial function and depict the importance of this interaction in cancer progression to metastasis.
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关键词
Genomic instability, chromatin, mitochondrial homeostasis, metabolism, cancer
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