Biosynthesis gene cluster of xantholipin

The invention relates to a biosynthesis gene cluster of xantholipin in the technical field of biomedicine, which comprises nucleotide sequences of 49 genes or complementary sequences formed by the sequences 1, wherein 29 genes are in charge of synthesizing a carbon framework and translationally modifying the carbon framework; 8 genes are in charge of providing a carbon framework extending unit and a methyl donor during the translational modification; 3 genes are in charge of providing resistance for host bacteria; and 6 genes exist in the biosynthesis process. The xantholipin generated in the invention has the functions of cloning, sequencing, analyzing and applying the biosynthesis gene cluster.