Liraglutide in combination with human umbilical cord mesenchymal stem cell could improve liver lesions by modulating TLR4/NF-kB inflammatory pathway and oxidative stress in T2DM/NAFLD rats.

Xiangjin Xu,Wenqing Wang,Lu Lin,Pin Chen

Tissue and Cell（2020）

引用 27|浏览10

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摘要

•Liraglutide and hUC-MSCs can improve the regulation of T2DM with NAFLD.•The mechanism was related to the TLR4/NF-κB inflammatory pathway and oxidative stress.•There is no such basic research.

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关键词

Non-alcoholic fatty liver disease,Type 2 diabetes mellitus,Liraglutide,Human umbilical cord mesenchymal stem cell,TLR4/NF-κB,Oxidative stress

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