Pleiotropic and Epistatic Network-Based Discovery: Integrated Networks for Target Gene Discovery

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Keywords:
<italic>Multi-omic data layering</italic><italic>LOE Scores</italic><italic>Lines of Evidence Scores</italic><italic>GWAS</italic><italic>SNP correlation</italic>More(8+)

Abstract:

Biological organisms are complex systems that are composed of functional networks of interacting molecules and macromolecules. Complex phenotypes are the result of orchestrated, hierarchical, heterogeneous collections of expressed genomic variants. However, the effects of these variants are the result of historic selective pressure and cu...More

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