Towards automation in biologics production via Raman micro-spectroscopy, laser-induced forward cell transfer and surface-enhanced Raman spectroscopy

Elisabeth Jaeckle,Eva Brauchle,Nadine Nottrodt,Martin Wehner,Richard Lensing,Arnold Gillner,Katja Schenke-Layland,Monika Bach,Anke Burger-Kentischer

Journal of Biotechnology（2020）

引用 3|浏览17

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摘要

•High-producer cell-screening platform, based on label-free laser-based techniques.•Laser-induced forward transfer (LIFT).•Surface-enhanced Raman spectroscopy (SERS).•Combination of Raman micro-spectroscopy, SERS and LIFT in a single platform.•Fully automated system for cell line development for biopharmaceuticals manufacturing.

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关键词

CHO,FACS,GFP,IgG,LAB,LIFT,PCA,SERS,TLR4

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