MnSOD Ala16Val polymorphism in cognitive dysfunction in patients with epilepsy: A relationship with oxidative and inflammatory markers

Josi Arend,Aline Kegler,Ana Letícia Fornari Caprara,Patricia Gabbi,Eduardo T Pascotini, Lori Ane Vargas de Freitas,Marta M M F Duarte,Núbia Broetto,Ana Flavia Furian,Mauro Schneider Oliveira,Luiz Fernando Freire Royes,Michele Rechia Fighera

Epilepsy & Behavior（2020）

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摘要

•Inflammatory disorders are more susceptible to MnSOD Ala16Val polymorphism in patients with epilepsy.•Cognitive deficit in MnSOD Ala16Val polymorphism in patients with epilepsy.•Oxidative pathway may be associated with genetic polymorphism in patients with epilepsy.

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关键词

MnSOD Ala16Val polymorphism,Epilepsy,Inflammation,Neuropsychological profile,Oxidative stress

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