Etiologic Index — A Case Only Measure of BRCA1/2–Associated Cancer Risk

Raymond Hughley,Rosa Karlic,Himanshu Joshi,Clare Turnbull,William D Foulkes,Paz Polak

NEW ENGLAND JOURNAL OF MEDICINE（2020）

引用 12|浏览25

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摘要

A proposed etiologic index, based on genomic variation in tumor cells and matched normal cells, suggests the possibility of involvement of variant BRCA1 and BRCA2 in types of cancer other than those with the "established" tumor types, such as breast cancer.

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