The limitations of the Cepheid GeneXpert® Mtb/Rif assay for the diagnosis and management of polyresistant pulmonary tuberculosis

Dahlia Hopmeier,Temi Lampejo, Julian Rycroft,Simon Tiberi,Mark Melzer

Clinical Infection in Practice（2020）

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摘要

•The absence of rpoB mutations does not rule out polyresistant TB.•There are no guidelines for lifting respiratory isolation in polyresistant TB.•Sputum samples may remain smear-positive for AFB but be culture-negative.

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关键词

Polyresistant TB,Resistance genotyping,Cepheid GeneXpert® Mtb/Rif

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