Sleep Architecture in Patients with Idiopathic Epilepsy

Sleep and Vigilance(2019)

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摘要
Purpose Studying the effects of epilepsy on sleep and its architecture and sleep on the epilepsy activity using sleep questionnaires, electroencephalogram (EEG), and polysomnogram (PSG) in patients with idiopathic epilepsy. Methods 25 patients with idiopathic epilepsy and 25 healthy controls ( M : F = 12:13; age: 21.32 ± 4.23 years) underwent assessment with sleep questionnaires, EEG and overnight PSG. Statistical Package for the Social Sciences vs.21 was used for statistical analysis. A ‘ p ’ b 0.05 was considered as statistically significant. Results There was poor sleep quality in patients compared to controls ( p = 0.02), while there was no significant difference in Epworth sleepiness scale scores between the groups. There was poor sleep quality in patients with idiopathic epilepsy compared to controls. Conclusion Patients with epilepsy activity had poor sleep quality in comparison to those with controlled disease status. Patients with juvenile myoclonic epilepsy showed initial insomnia as they had significant increase in sleep onset latency in comparison with other patients with idiopathic generalized epilepsy.
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关键词
Epileptic activity,Parasomnia,Periodic limb movement,Refractory epilepsy,Antiepileptic drugs,Deep sleep
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