The diagnostic value of serum C-reactive protein, procalcitonin, interleukin-6 and lactate dehydrogenase in patients with severe acute pancreatitis

•Mortality of severe acute pancreatitis is up to 50% lack of early diagnosis.•Detection of PCT, CRP, IL-6 and LDH was low costs, high reproducibility.•A worthful approach might be to use a combination of serum PCT, CRP, IL-6 and LDH in severe Acute Pancreatitis.