Construction of CuS@Fe-MOF nanoplatforms for MRI-guided synergistic photothermal-chemo therapy of tumors

Zhaojie Wang,Wanjian Yu,Nuo Yu,Xuan Li, Yirou Feng,Peng Geng,Mei Wen,Maoquan Li,Haijun Zhang,Zhigang Chen

Chemical Engineering Journal（2020）

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摘要

•In-situ growth of Fe-MOF shell on CuS nanoplates.•Strong NIR photoabsorption and photothermal conversion efficiency (39.7%) due to CuS core.•High drug loading efficiency (27.5%), pH-responsive releasing ability and MR imaging ability due to Fe-MOF shell.•Efficiency treatment of tumors by synergistic photothermal-chemo therapy of CuS@Fe-MOF.

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关键词

CuS,Photothermal ablation therapy,Chemotherapy,Metal-organic framework

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