Lymphoblastic predominance of blastic phase in children with chronic myeloid leukaemia treated with imatinib: A report from the I-CML-Ped Study

Deborah Meyran,Arnaud Petit,Joelle Guilhot,Meinolf Suttorp,Petr Sedlacek,Eveline De Bont,Chi Kong Li,Krzysztof Kalwak,Birgitte Lausen,Srdjana Culic,Barbara de Moerloose,Andrea Biondi,Frédéric Millot

European Journal of Cancer（2020）

引用 6|浏览33

暂无评分

摘要

•Progression of chronic myeloid leukaemia in children under imatinib treatment.•Incidence of progression at 1 and 3 years is 3% and 7%, respectively.•Lymphoid phenotype predominance in blastic phase with upfront imatinib treatment.•Poor outcome when transformation occurs while on tyrosine kinase inhibitor therapy.

查看译文

关键词

Chronic myeloid leukaemia,Children,Accelerated phase,Blastic phase,Tyrosine kinase inhibitors,Haematopoietic stem cell transplantation

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要