IgG stimulated β2 adrenergic receptor activation is attenuated in patients with ME/CFS

Jelka Hartwig,Franziska Sotzny,Sandra Bauer,Harald Heidecke,Gabriela Riemekasten,Duska Dragun,Christian Meisel,Claudia Dames,Patricia Grabowski,Carmen Scheibenbogen

Brain, Behavior, & Immunity - Health（2020）

引用 20|浏览28

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摘要

•IgG physiologically stimulates β2 AdR signaling.•β2 AdR activation by IgG is attenuated in ME/CFS patients.•First evidence that IgG from ME/CFS patients differentially modulates β2 AdR ligand signaling.

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关键词

IgG,β2 adrenergic receptor,Autoantibodies,Myalgic encephalomyelitis,Chronic fatigue syndrome

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