The ACTN3 577XX Null Genotype Is Associated with Low Left Ventricular Dilation-Free Survival Rate in Patients with Duchenne Muscular Dystrophy

•The ACTN3 genotype is a genetic modifier for Duchenne muscular dystrophy.•The ACTN3 genotype with risk of dilated cardiomyopathy in patients was studied.•The ACTN3 577XX null genotype has a low left ventricular dilation-free survival rate.•The ACTN3 577XX null genotype is a risk factor for left ventricular dilation.