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Screening of a Custom-Designed Acid Fragment Library Identifies 1-Phenylpyrroles and 1-Phenylpyrrolidines As Inhibitors of Notum Carboxylesterase Activity.

William Mahy, Mikesh Patel,David Steadman,Hannah L. Woodward,Benjamin N. Atkinson,Fredrik Svensson,Nicky J. Willis, Alister Flint, Dimitra Papatheodorou,Yuguang Zhao,Luca Vecchia,Reinis R. Ruza,James Hillier,Sarah Frew,Amy Monaghan,Artur Costa,Magda Bictash,Magnus W. Walter,E. Yvonne Jones,Paul V. Fish

JOURNAL OF MEDICINAL CHEMISTRY（2020）

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关键词
Enantioselective Synthesis
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