Semi-automatic detection of increased susceptibility in multiple sclerosis white matter lesions imaged with 1.5T MRI.

•We propose a semi-automatic method to detect regions of increased susceptibility within MS WM lesions on 1.5 T MRI data.•The method proved to be sensitive and specific in detecting regions of increased susceptibility within MS WM lesions.•The number of WM lesions with regions of increased susceptibility correlated with disease duration in MS.