Characterization, antibiofilm and biocompatibility properties of chitosan hydrogels loaded with silver nanoparticles and ampicillin: an alternative protection to central venous catheters

Colloids and Surfaces B: Biointerfaces(2020)

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摘要
•New chitosan hydrogels with silver nanoparticles and ampicillin were prepared.•Antibiofilm activity against multidrug-resistant pathogens is reported.•New chitosan hydrogels are a strategy for biofilm control having low cytotoxicity.•Potential to prevent colonization and thrombosis on central venous catheter is studied.
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关键词
Biofilm,central venous catheter,chitosan,cytotoxicity,silver nanoparticles,hemostatic properties
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