Autophagy-related gene expression classification defines three molecular subtypes with distinct clinical and microenvironment cell infiltration characteristics in colon cancer
International Immunopharmacology(2020)
摘要
•Three autophagy-related molecular subtypes with distinct clinical outcomes were determined in colon cancer.•Three autophagy subtypes presented significant heterogeneity in TME immune cell infiltration.•The values of APCS signature in predicting patient prognosis and immunotherapeutic responses were confirmed.
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关键词
Autophagy,Molecular subtypes,Tumor microenvironment,Immunotherapy,Colon cancer
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