HPV11E7 inhibits IMQ-induced chemokine and colony-stimulating factor production in keratinocytes

Huimin Zheng,Ziqi Zou,Xia Wu,Yaohan Xu,Jiang Zhu,Qiang Zhou,Rui Han,Yinjing Song,Hao Cheng

Gene（2020）

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摘要

•IMQ upregulates the expression of chemokines and colony-stimulating factors in keratinocytes.•IMQ treatment alters the expression profile of metabolism-related genes.•IMQ treatment regulates the expression profile of cytokine signaling pathway-related genes.•HPV11E7 inhibits IMQ-induced cytokine production by impairing the MAPK signaling pathway in keratinocytes.

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关键词

Imiquimod,HPV11E7,RNA-seq,Chemokine,Colony-stimulating factor,MAPK signaling pathway

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