HUVEC support bone formation of ADSC-loaded and 3D-printed osteogenic matrices in the AV loop model.

Sophie Winkler,Hilkea Mutschall,Jonas Biggemann,Tobias Fey,Peter Greil,Carolin Körner,Volker Weisbach,Andrea Meyer-Lindenberg,Andreas Arkudas,Raymund E Horch,Dominik Steiner

Tissue engineering. Part A（2020）

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摘要

Vascularization and bone formation of osteogenic matrices consisting of ADSC and HUVEC in the rat AV loop model could be demonstrated successfully for the first time. Hence, the co-implantation of differentiated ADSC with HUVEC may therefore be considered as a promising approach for bone tissue engineering.

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关键词

bone tissue engineering, AVL model, ADSC, HUVEC, osteogenesis, angiogenesis

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