Synthesis of N , N '-Disubstituted Dithiooxamide Derivatives by the Modified Willgerodt–Kindler Reaction

The conditions of the reaction of trichloroethylene with sulfur and amines were optimized (the modified Willgerodt–Kindler reaction). The reaction of tetrachloroethylene with sulfur and some basic primary and secondary amines of the aliphatic series in DMF under mild conditions leads to N , N '-disubstituted dithiooxamides in 30–70% yields and with a 100% conversion of tetrachloroethylene.