Molecular diagnosis of epileptic encephalopathy of the first year of life applying a customized gene panel in a group of Argentinean patients.

•A targeted NGS panel was designed to analyse a group of 17 Argentinean patients with EEs of the first year of life•A genetic diagnosis was identified in ∼50% of the patients, 87% of them presenting with a non-previously reported variant.•Molecular diagnosis in EE Latin American patients is relevant to increase our knowledge about our own mutational spectrum.•NGS diagnosis will be available for the patients with epilepsy attending a public tertiary paediatric hospital.