Impact of Fiber-Based Enteral Nutrition on the Gut Microbiome of ICU Patients Receiving Broad-Spectrum Antibiotics: A Randomized Pilot Trial.

Daniel E Freedberg, Megan Messina,Elissa Lynch, Monika Tess,Elizabeth Miracle,David H Chong, Romina Wahab,Julian A Abrams,Harris H Wang,Christian Munck

Critical care explorations（2020）

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摘要

Enteral fiber was associated with nonsignificant trends toward increased relative abundance of short-chain fatty acid-producing bacteria and increased short-chain fatty acid levels among ICU patients receiving broad-spectrum IV antibiotics. Larger studies should be undertaken and our results can be used for effect size estimates.

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关键词

Clinical Trial, colonization,ICU,antimicrobial resistance,fiber,microbiome,nutrition,prebiotics,probiotics,sepsis,short-chain fatty acids

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