The Role of Dihydropyrimidine Dehydrogenase and Thymidylate Synthase Polymorphisms in Fluoropyrimidine-Based Cancer Chemotherapy in an Iranian Population.

gene polymorphisms may play a key role in fluoropyrimidne -based chemotherapy. Although rare polymorphisms were not observed in our study, according to large population studies, gene polymorphisms could be used as a predictive biomarker for patient treatments.