Post-mortem 7 Tesla MRI detection of white matter hyperintensities: A multidisciplinary voxel-wise comparison of imaging and histological correlates.

Austyn D Roseborough,Kristopher D Langdon,Robert Hammond,Lauren E Cipriano,Stephen H Pasternak,Shawn N Whitehead,Ali R Khan

NeuroImage: Clinical（2020）

引用 13|浏览8

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摘要

•Ultra high-field post mortem MRI is a valid tool for the study of white matter hyperintensities.•Demyelination and parenchymal rarefaction are associated with FLAIR and T2 changes on 7 Tesla MRI.•Age, length of fixation and pathological diagnosis are all significant predictors of white matter FLAIR voxel intensity.

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关键词

AD,CVD,FLAIR,MRI,SVD,UHF,WMH

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