Octreotide alleviates pancreatic damage caused by paraquat in rats by reducing inflammatory responses and oxidative stress.

Yanxia Gao,Linlin Hou,Yibo Wang,Shigong Guo,Ding Yuan, Ya'nan Jiang,Guoyu Duan,Yan Zhang,Zhigao Xu,Lu Che,Changhua Sun,Sujuan Li,Shoutao Zhang,Tongwen Sun,Yi Li

Environmental Toxicology and Pharmacology（2020）

引用 13|浏览6

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摘要

•Paraquat can cause pancreatic injury.•Octreotide could mitigate paraquat-induced systemic inflammatory response.•Octreotide can antagonize the pancreatic injury via NF-κB signaling pathway.

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关键词

Paraquat,Octreotide,Pancreas,Nuclear factor kappa B p65,Nuclear factor erythroid 2–related factor 2

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