EURL ECVAM Genotoxicity and Carcinogenicity Database of Substances Eliciting Negative Results in the Ames Test: Construction of the Database.

Federica Madia,David Kirkland,Takeshi Morita,Paul White,David Asturiol,Raffaella Corvi

Mutation Research/Genetic Toxicology and Environmental Mutagenesis（2020）

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摘要

•EURL ECVAM Consolidated Genotoxicity and Carcinogenicity Database extended.•Negative Ames test results were compiled and reviewed.•A database of Ames negative results was constructed.•Database chemical space characterization was conducted.•OFG representation of carcinogens and non-carcinogens was characterised.

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关键词

Carc,CAvit,CAviv,CCRIS,CGX,CPDB,CSCL,CTA,DNAviv,ECHA,EFSA,EURL ECVAM,GENE-TOX,Hprt,HSDB,HESI GTTC,IARC,ISHL,JETOC,MCGM,MLA,MNvit,MNviv,NTP,OECD,OECD SIDS,OFG,QSAR,SCE,SCCS,TGR,UDSviv

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