Serum latent transforming growth factor-β binding protein 4 as a novel biomarker for idiopathic pleuroparenchymal fibroelastosis.

Yoshiaki Kinoshita,Takato Ikeda,Hisako Kushima,Masaki Fujita,Tomoyuki Nakamura,Kazuki Nabeshima,Hiroshi Ishii

Respiratory Medicine（2020）

引用 7|浏览64

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摘要

•LTBP-4 levels in lung tissue of IPPFE patients were higher than in IPF patients.•Serum LTBP-4 levels in IPPFE patients were higher than in healthy controls.•A higher serum LTBP-4 level was associated with a poor prognosis in IPPFE patients.

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关键词

Idiopathic pulmonary fibrosis,Elastic fibers,Elastogenesis,Krebs von den Lungen-6,Elastosis

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